This episode looks at pioneering treatments for some of the oldest and youngest patients in the hospital. A 98-year-old man arrives at Hammersmith Hospital for a landmark heart operation. The operation known as TAVI is offered to patients who are deemed not suitable for open heart surgery. Without the op, John has been told he has only a 50 percent chance of surviving the next six months. The clock is also ticking for 18-year-old Debbie at St Mary's Hospital, home to the Trust's specialist paediatric centre. Debbie is about to have a lifesaving bone marrow transplant which could cure her of sickle cell disease.

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